10 Best Generic Effervescent Antacid Tablets of 2026

Why We Love It

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  Fast Heartburn + Pain Relief: Alka-Seltzer's 2-in-1 effervescent aspirin + antacid tablets for relief of heartburn with pain symptoms
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  Nothing Works Faster: Dissolves quickly in water and starts working fast to relieve pain and neutralize stomach acid for quick heartburn and acid indigestion relief
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  Contains aspirin: Provides fast relief of pain symptoms including headaches, back pain, muscle pain, and body pain
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  Easy-to-Carry Sachets: This travel-friendly pack includes 36 individual packets of aspirin + antacid tablets. Designed for easy storage, so quick pain + heartburn relief are always within reach
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  How to use: Fully dissolve 2 tablets in 4oz of water, fizz it and drink it. You do not have to drink any of the residue that may be on the bottom of the glass. The medicines of Alka-Seltzer Heartburn + Pain Relief are in the water
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  Trusted for Over 90 Years: Your go-to brand for fast pain and heartburn relief since 1931

Main Highlights

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  Helps relieve heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains
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  Effective on upset stomach with headache resulting from overindulgence in food or drink
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  Works fast for proven, time-tested relief
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  Contains 24 tablets
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  Please read all label information on delivery

Main Highlights

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  Relieves heartburn, acid indigestion, sour stomach, and upset stomach.
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  150 chewable tablets per package.
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  Assorted Fruit flavor.
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  Active Ingredient: 500mg of Calcium Carbonate (Antacid).
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  Compare to other leading brand antacids.

Main Highlights

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  RAPID ACID RELIEF: Experience fast and effective relief from heartburn and indigestion with our sodium bicarbonate tablets. Specially formulated for quick neutralization of excess stomach acid, providing prompt comfort.
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  GENTLE ON YOUR STOMACH: Our tablets are crafted with a gentle yet powerful formula, ensuring relief without causing irritation. Ideal for those with sensitive stomachs, offering a soothing solution to digestive discomfort.
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  ON-THE-GO CONVENIENCE: Convenient and portable tablets for instant relief wherever you are. Perfect for busy lifestyles, travel, or any time you need quick and reliable antacid support.
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  PHARMACEUTICAL-GRADE QUALITY: Trust in the quality of our pharmaceutical-grade sodium bicarbonate tablets. Manufactured to rigorous standards, guaranteeing safety, purity, and optimal performance.
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  VERSATILE DIGESTIVE SUPPORT: Beyond heartburn relief, our tablets contribute to overall digestive health. Balances pH levels to reduce bloating and gas, promoting a comfortable and healthy digestive system.

Main Highlights

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  TRUSTED RELIEF: Sal Andrews Salts are a well-known sparkling antacid formula designed to relieve upset stomach, heartburn, and acid indigestion.
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  ORANGE FLAVOR: Each tablet features a refreshing orange flavor, making it a pleasant and easy way to address common digestive discomforts.
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  CONVENIENT PACKAGING: Comes in a box of 12 individual tablets, making it easy to store at home or carry on the go for fast relief when needed.
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  SPARKLING FORMULA: The effervescent sparkling salt formula works quickly to help neutralize excess stomach acid for prompt digestive comfort.
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  EASY TO USE: Simply take a tablet as directed to experience soothing relief from upset stomach, heartburn, and acid indigestion symptoms.

Main Highlights

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  Ultra Strength Antacid Chewable Tablets, Assorted Fruit, 10/Roll, 12 Roll/Box

Main Highlights

Main Highlights

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  Equate Extra Strength Antacid Chewable Wintergreen Tablets 750 mg, 96 Ct Pack of 01
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  Equate Extra Strength Sugar-Free Antacid Chewable Tablets, Orange Cream,750 mg 90 Count pack of 01
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  Extra Strength Sugar-Free Antacid Chewable Tablets, Orange Cream,750 mg
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  Extra Strength Antacid Chewable Wintergreen Tablets 750 mg,
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  Sugar-Free Antacid Chewable Tablets, Orange Cream,750 mg 90 Count

Main Highlights

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  Equate Ultra Strength Antacid Chewable Fruit Tablets,1000 mg, 72 Ct Pack of 03 216 Total Includes Pill Organizer
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  Equate Ultra Strength Antacid Chewable Fruit Tablets,1000 mg, 72 Ct Pack of 03
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  Ultra Strength Antacid Chewable Fruit Tablets,1000 mg, 72 Ct Pack of 03 216 Total
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  Antacid Chewable Fruit Tablets,1000 mg
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  Pack of 03 216 Total Includes Pill Organizer

Main Highlights

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  Take Alka-Seltzer any time - morning, noon, or night - when you need relief from acid indigestion, upset stomach, or heartburn with headache or body aches and pains
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  Alka-Seltzer